Keywords: Data Processing, Elastography
Motivation: Advancements in diffusion MRI enable more complete characterization of white matter tracts with magnetic resonance elastography-derived properties via tractometry.
Goal(s): We apply tractometry to measure tract shear stiffness and damping ratio.
Approach: For a sample of 44 adults, MRE measures were co-registered to tractogram space and sampled, along with diffusion scalars.
Results: Patterns in both shear stiffness and damping ratio were not strongly explained by diffusion metrics in either the corpus callosum or the superior longitudinal fasciculus. This highlights that while shear stiffness has some spatial relationship with diffusion anisotropy, elastography provides unique structural information with limited mutual information from diffusion MRI.
Impact: As biomarker discovery continues to incorporate the more spatially informative tract profiles from tractometry, this approach offers researchers and clinicians the ability to spatially sample both diffusion- and elastography-based structural information to better characterize white matter tract structural health.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords