Abstract #3294

Rapid Acquisition of the Gradient Impulse Response Function using a Cryo-coil at 9.4 T

Alexander Jaffray¹, Andrew Yung², Oliver Goedlicke³, Stefan Reinsberg¹, and Alexander Rauscher^1,4

¹Department of Physics, University of British Columbia, Vancouver, BC, Canada, ²Department of Radiology, University of British Columbia, Vancouver, BC, Canada, ³Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany, ⁴Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada

Synopsis

Keywords: System Imperfections, Preclinical, Gradient Impulse Response Function, GIRF

Motivation: Phantom-based gradient impulse response function (GIRF) measurements can characterize pre-clinical MRI gradient system changes, however duration may prohibit frequent GIRF measurement.

Goal(s): Development of a fast phantom-based GIRF acquisition protocol for pre-clinical 9.4 T MRI systems using a cryo-probe and optimized phantom.

Approach: A spherical phantom with shortened T₁ was developed with cryo-probe and GIRF compatible geometry. A modified gradient blip scheme was developed and compared against a reference GIRF acquisition strategy.

Results: Using a cryo-probe, short T₁ (37 ms) and a minimal blip pattern, a GIRF acquisition time of 2.36 seconds per gradient channel was achieved at 9.4 T.

Impact: Pre-clinical MR imaging systems often use application-specific hardware configurations which may influence mechanical resonances and system performance. A rapid GIRF acquisition protocol will streamline frequent system characterization. Rapid GIRF acquisition may enable new strategies for probing gradient system linearity.

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