Keywords: Hybrid & Novel Systems Technology, Hybrid & Novel Systems Technology
Motivation: Perform simultaneous EEG and fMRI using a compact and wireless detector that can continuously record EEG signals in the presence of switching gradients.
Goal(s): However, MRI scanners generate tremendous artifacts for EEG detection.
Approach: A Wireless Integrated Sensing Detector for simultaneous EEG and MRI (WISDEM) is developed to encode fMRI and EEG signals on distinct sidebands of the detector’s oscillation carrier wave for detection by a standard MRI console over the entire duration of fMRI sequence.
Results: From optogenetically-stimulated somatosensory cortex, the positive correlation between evoked LFP and fMRI signals validates strong neurovascular coupling.
Impact: This 2-in-1 transducer will enable cross-scale brain mapping.
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