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Abstract #3361

Single breath-hold lung T2* mapping using multi-echo 3D spiral UTE with tight interval δTE

Jun Zhao1,2, Yupeng Cao3, Wentao Liu1, Qian Zeng1, Siqi Wang1,2, Hongbin Wang3, Weinan Tang3, and Dong Han1
1CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, China, 2School of Future Technology, University of Chinese Academy of Sciences, Beijing, China, 3Beijing Wandong Medical Technology Co., Ltd, Beijing, China

Synopsis

Keywords: New Trajectories & Spatial Encoding Methods, Lung, T2* mapping, breath-hold, spiral, UTE

Motivation: Single-echo lung T2* mapping requires multiple images at different echo times, leading to long scan times and potential registration issues. While multi-echo sequences reduce scan time by acquiring multiple echoes in one shot, the echo intervals remain too long for lung short T2*.

Goal(s): We aim to shorten the echo intervals within a single breath-hold to enable quantitative lung T2* mapping.

Approach: We performed a segmented readout in the radial-spiral hybrid trajectory.

Results: As a result, our proposed method enables single breath-hold (15 s) lung T2* quantification with an echo interval of 0.57 ms and in-plane resolution of 2 mm.

Impact: Our proposed method enables single breath-hold lung T2* quantification with a 0.57 ms echo interval and 2 mm in-plane resolution. Rapid and accurate T2* assessment in the lungs is crucial for evaluating structural and functional changes caused by lung diseases.

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Keywords