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Abstract #3365

Combined caLculation of Ultra-high field Biases (CLUB) with Sandwich: fast, simultaneous estimation of 3D B0 and multi-channel B1+ maps for 7T MRI

Natalia Pato Montemayor1,2,3, Jocelyn Philippe1,2,3, James L. Kent4, Aaron Hess4, Antoine Klauser1, Emilie Sleight5,6, Lina Bacha1,2,3, Tommaso Di Noto1,2,3, Bénédicte Maréchal1,2,3, Patrick A. Liebig7, Jürgen Herrler7, Dominik Nickel7, Robin M. Heidemann7, Jean-Philippe Tiran2,3, Tobias Kober7, Tom Hilbert1,2,3, Thomas Yu1,2,3, and Gian Franco Piredda1
1Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, 2LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 3Department of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 4Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 5CIBM Centre for Biomedical Imaging, Geneva, Switzerland, 6Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 7Siemens Healthineers AG, Erlangen, Germany

Synopsis

Keywords: Pulse Sequence Design, System Imperfections: Measurement & Correction, B0 & B1 Mapping, 7T

Motivation: More efficient mapping of magnetic field inhomogeneities (B0 and B1+) is essential in ultra-high field MRI for individually optimizing parallel transmission pulses.

Goal(s): To rapidly, simultaneously, and accurately estimate B0 and B1+ inhomogeneities at 7T.

Approach: We propose a modification of the 3D B1+ mapping Sandwich sequence (CLUB-Sandwich), which integrates three monopolar echoes for ΔB0 mapping in the pre-saturation train. The CLUB-Sandwich approach is validated by comparing the estimated ΔB0 and B1+ maps to standard reference methods in five subjects.

Results: Minimal differences (mean bias of 0.9$$$\,$$$±$$$\,$$$4.5 Hz and 3.2$$$\,$$$±$$$\,$$$1.1°) demonstrate reliable, fast mapping of ultra-high field inhomogeneities.

Impact: The proposed CLUB-Sandwich sequence enables rapid, simultaneous ΔB0 and B1+ mapping at 7T without accuracy reduction, providing a faster method for optimizing parallel transmission pulses, increasing efficiency in ultra-high field MRI applications.

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Abstract

Keywords