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Abstract #3374

Do second-order motion-compensation gradients and spiral sampling suppress phase variations in DWI?

Wen Zhong1, Yuancheng Jiang1, and Hua Guo1
1Center for Biomedical Imaging Research, School of Biomedical Engineering, Tsinghua University, Beijing, China

Synopsis

Keywords: Pulse Sequence Design, Diffusion Acquisition, Stack of spirals, motion compensation, pulse sequence

Motivation: Phase variation introduces complexity to multishot 2D or 3D DWI. Using second-order motion-compensation (MC2) gradients and peripheral pulse unit (PPU) trigger, single-slab whole-brain 3D EPI DWI shows promise. We aim to test whether stack of spiral(3D spiral) using MC2 avoid phase variation without trigger.

Goal(s): To test the performance of motion-compensated 3D spiral imaging without trigger.

Approach: We acquired whole-brain DWI data using motion-compensated 3D spiral with and without trigger, and collected 2D SMS EPI data for reference.

Results: Without trigger, 3D spiral showed instable image quality using direction reconstruction, while with trigger, 3D spiral eliminated phase variation, resulting in better reconstruction.

Impact: This study confirms the necessity of trigger in motion-compensated stack of spiral, as whole-brain single-slab DWI cannot be achieved without it.

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