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Abstract #3376

Designing MR Exams Using an Autonomous Multi-Agent Large Language Model System

Anuj Sharma1, William A Grissom1, and Mark A Griswold2
1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2Radiology, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: Language Models, Language Models, AI/ML Software

Motivation: There is a global shortage of radiology staff which can lead to workforce burnout, increased backlogs and healthcare costs. AI-based workflow automation can help mitigate some of these effects.

Goal(s): To develop an autonomous large language model system that can generate MR pulse sequences customized to the patient’s electronic health record.

Approach: We developed a multi-agent system that takes natural language prompts and produces scanner-executable Pulseq sequences via EHR database queries and customized MR protocol generation. The system was validated using the MIMIC-IV database.

Results: The multi-agent system successfully generated patient-specific pulse sequences that achieved desired tissue contrast in brain imaging.

Impact: MR exam delivery is challenged by a worldwide shortage of radiology staff. We demonstrate that a multi-agent LLM system shows promise in automating MR exams by accessing a patient’s health record and designing the protocol and sequences to be acquired.

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Keywords