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Abstract #3436

Does Phase-Based EPT with a Noise-Robust Method Provide Similar Results for GRE and bSSFP Acquisitions?

Oriana V. Arsenov1, Jierong Luo1, and Karin Shmueli1
1Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

Synopsis

Keywords: Electromagnetic Tissue Properties, Acquisition Methods, Phase-based EPT, Electrical Properties Tomography, Electrical Conductivity, MR-EPT

Motivation: The MagSeg phase-based electrical properties tomography (EPT) method has been shown to reduce noise in GRE but demonstrating its performance for ‘gold-standard’ bSSFP would broaden its applicability.

Goal(s): To investigate the performance of the MagSeg method for bSSFP and GRE.

Approach: MagSeg was optimised for each acquisition using a numerical phantom with SNR matched to in-vivo brain data. Tissue conductivity differences were compared for the two acquisitions.

Results: MagSeg provided high-quality EPT with clear delineation between different tissue types. bSSFP had slightly lower gray-white matter EPT contrast than GRE, but higher, albeit noiser, CSF conductivities, with a mean closer to values measured ex-vivo.

Impact: Using the noise-robust MagSeg method for phase-based EPT in GRE and bSSFP acquisitions provided similar high-quality conductivity maps. This performance for the ‘gold-standard’ bSSFP acquisition provides validation of this method and a basis for a wide range of applications.

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