Abstract #3512

Impact of transcatheter aortic valve replacement on blood flow and fluid dynamics in the aorta and brachiocephalic artery

Koji Yamasaki¹, Satonori Tsuneta^1,2, Motoma Kanaya¹, Suguru Ishizaka³, Kiwamu Kamiya³, Toshiyuki Nagai³, Toshihisa Anzai³, and Kohsuke Kudo⁴

¹Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ²Oral Health Science, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan, ³Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁴Diagnostic Imaging, Hokkaido University Graduate School of Medicine; Global Center for Biodedical Science and Engieering, Faculty of Medicine, Hokkaido University, Sapporo, Japan

Synopsis

Keywords: Vascular/Vessel Wall, Cardiovascular

Motivation: Changes in blood flow and fluid dynamics of the ascending aorta (AsAo) and brachiocephalic artery (BCA) after transcatheter aortic valve replacement (TAVR) for severe aortic stenosis (AS) are not clear.

Goal(s): To investigate the changes in blood flow and fluid dynamics in the AsAo and BCA before and after TAVR.

Approach: Blood flow and fluid dynamics were evaluated using four-dimensional flow magnetic resonance imaging (4D flow MRI) before and after TAVR.

Results: 4D flow MRI revealed a significant increase in blood flow at the BCA, especially in low flow AS, and improvement in fluid dynamics parameters at the AsAo.

Impact: 4D flow MRI revealed changes in blood flow and fluid dynamics of the AsAo and BCA before and after TAVR. 4D flow MRI may be a potential tool to comprehensively evaluate perioperative blood flow dynamics for severe AS.

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