Meeting Banner
Abstract #3517

Quantifying Hepatic Arterial Blood Flow with 4D Flow MRI to Improve Transarterial Radioembolization: a Feasibility and Repeatability Study

Anne van den Brekel1, Marnix C Maas1, Ilse M Spenkelink1, Willem C M van Tilburg1, Joey Roosen1, Daniel Giese2, Ning Jin3, Jurgen J Fütterer1, and J Frank W Nijsen1
1Department of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands, 2Magnetic Resonance, Siemens Healthineers AG, Forchheim, Germany, 3Cardiovascular MR R&D, Siemens Medical Solutions USA, Malvern, PA, United States

Synopsis

Keywords: Flow, Velocity & Flow, 4D flow, phase-contrast, feasibility, repeatability, radioembolization

Motivation: Hepatic arterial blood flow (HABF) is expected to be an important parameter influencing the microsphere distribution during transarterial radioembolization (TARE).

Goal(s): This study aimed to assess the ability of 4D flow MRI (3D time-resolved phase-contrast MRI with 3D velocity encoding) to quantify HABF.

Approach: An in vivo feasibility and repeatability (scan-rescan reliability) study was conducted in twenty volunteers, followed by a feasibility study in ten patients with a liver disease.

Results: Quantifying HABF with 4D flow MRI is feasible, but there are large variations in scan-rescan reliability. Further analyses are planned to understand the (variation in) scan-rescan differences.

Impact: If hepatic arterial blood flow (HABF) quantification with 4D flow MRI proves feasible and repeatable, the technique can be used to investigate the relationship between HABF and transarterial radioembolization (TARE) microsphere distribution, with the ultimate goal of improving TARE outcomes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords