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Abstract #3544

Brain T1 Relaxation Time Changes After Acute Exercise

Xinyuan Hu1,2, Zijian Zhou1,2, Haikun Qi1,2, Wenchao Yang3, and Peng Hu1,2
1School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, 2Shanghai Clinical Research and Trial Center, Shanghai, China, 3Central Research Institute, United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Relaxometry, Brain, Acute Exercise, T1 Mapping

Motivation: Brain T1 relaxation time changes following a single session of acute exercise has not been investigated.

Goal(s): This study aims to investigate the effects of a single session of aerobic exercise on brain T1.

Approach: A magnetic resonance imaging (MRI) T1 mapping sequence was used to measure the global and regional brain T1 before and after 8-15 minutes of cycling exercise in 18 healthy subjects.

Results: The global and regional brain T1 was generally deceased right after exercise and started to recover shortly. However, T1 of the left insula and certain areas of the temporal poles was significantly increased.

Impact: We found that a single session of aerobic exercise can induce significant and region-specific T1 changes in the brain, offering a novel perspective for brain studies in addition to current functional and perfusion MRI.

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