Abstract #3582

Choroid Plexus Radiomics for Differentiating MS and NMOSD and Their Correlation with Clinical Characteristics

Xiaohua Wang^1,2, Xiaolong Wang ³, Yanbing Liu⁴, and Yongmei Li²

¹Department of Radiology, The First Affiliated Hospital of Chongqing Medical University; Chongqing Medical University, Chongqing, China, ²Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, ³College of Computer and Information Science, Southwest University, Chongqing, China, ⁴College of Medical Informatics, Chongqing Medical University, Chongqing, China

Synopsis

Keywords: Multiple Sclerosis, Multiple Sclerosis, Choroid Plexus

Motivation: This study aims to deepen understanding of abnormalities in the choroid plexus (CP) associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), providing a foundation for elucidating their underlying pathogenic mechanisms and developing targeted treatments.

Goal(s): To investigate and compare radiomics features of the CP in MS and NMOSD for clinical insights.

Approach: A retrospective analysis was conducted, extracting CP radiomics features from 3D T1-weighted images and employing statistical methods and machine learning.

Results: Significant differences in CP features were identified, with implications for differentiating MS from NMOSD and correlations with clinical characteristics.

Impact: This research advances the understanding of CP abnormalities in MS and NMOSD, aiding differential diagnosis and clinical monitoring.

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