Meeting Banner
Abstract #3609

The Vicious Cycle of Glymphatic Dysfunction, Chronic Inflammation, and Neurodegenerative Disorders

Qiuting Wen1, Liangjun Mao2, Jiani Hu2, and Quan Jiang3
1Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA, Indianapolis, IN, United States, 2Department of Radiology, School of Medicine, Wayne State University, Detroit, MI, USA, Detroit, MI, United States, 3Department of Neurology, Henry Ford Health System, Detroit, MI, USA, Detroit, MI, United States

Synopsis

Keywords: Neuroinflammation, Neurodegeneration

Motivation: The study is motivated by the need to understand why an impaired glymphatic system contributes to the pathogenesis of nearly all neurodegenerative disorders.

Goal(s): The objective is to demonstrate that chronic inflammation, glymphatic dysfunction, and neurodegenerative disorders form a vicious cycle

Approach: A comprehensive literature review and analysis of experimental data were conducted.

Results: Summarize key results of the study that show how well you achieved the goals: chronic inflammation, glymphatic dysfunction, and neurodegenerative disorders form a vicious cycle

Impact: It highlights how chronic inflammation facilitates the interplay between glymphatic dysfunction and neurodegenerative diseases. Disrupting this cycle could provide new therapeutic avenues for treating neurodegenerative conditions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords