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Abstract #3612

Third Trimester Fetal 4D Flow MRI with Motion Correction

Reagan M. Tompkins1, Takashi Fujiwara2, Eric M. Schrauben1, Lorna P. Browne2, Joost van Schuppen1, Sally-Ann Clur3, Richard M. Friesen4, Erin K. Englund2, Alex J. Barker2,5, and Pim van Ooij1
1Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands, 2Department of Radiology, Section of Pediatric Radiology, Children’s Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 3Department of Pediatric Cardiology, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, Netherlands, 4Department of Pediatrics, Section of Cardiology, Children’s Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 5Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

Synopsis

Keywords: Fetal, Fetal

Motivation: Fetal 4D flow MRI is limited by the presence of motion from maternal breathing and stochastic fetal movements

Goal(s): To demonstrate the effects of maternal respiratory and fetal bulk motion correction with outlier rejection in 4D flow MRI

Approach: One or more 4D flow datasets were acquired in 17 fetuses, followed by maternal respiratory gating and bulk motion correction, and compressed sensing (CS) reconstruction with outlier rejection. Uncorrected (CS without motion correction) reconstructions served as reference.

Results: Twenty-nine scans were evaluated. Motion correction recovered 8/13 heavily motion-corrupted scans, and provided improved conservation of mass values (uncorrected=14%(24%),corrected=5%(9%),p=0.002) at the ductal insertion at the aorta.

Impact: The proposed method of maternal respiratory gating and fetal bulk motion correction combined with data outlier rejection in fetal 4D flow led to a reduction in motion artifacts, recovery of previously corrupted scans, and improved conservation of mass.

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Abstract

Keywords