Abstract #3648
Evolution of the motor cortex microstructure and its lateralization: a comparative study of chimpanzees and humans
Maelig Chauvel1, Evgeniya Kirilina1, Ilona Lipp1, Carsten Jäger1,2, Kerrin Pine1, Luke Edwards1, Sonja Ebel3,4, Kathrin Kopp3,4, Saskia Helbling1,5, Peter McColgan6, Daniel Rose1, Tobias Gräßle7,8, Denis Chaimow1,9, Catherine Crockford10,11,12, Roman Wittig10,11,12, and Nikolaus Weiskopf1,13,14
1Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 2Paul Flechsig Institute - Center of Neuropathology and Brain Research, Faculty of Medicine, Universität Leipzig, Leipzig, Germany, 3Human Biology & Primate Cognition Group, Institute of Biology at Leipzig University, Leipzig, Germany, 4Department of Comparative Cultural Psychology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, 5Ernst Strüngmann Institute for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main, Germany, 6University College London, London, United Kingdom, 7Ecology and Emergence of Zoonotic Diseases, Helmholtz Institute for One Health, Helmholtz Centre for Infection Research, Greifswald, Germany, 8Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Berlin, Germany, 9Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 10Department of Human Behavior, Ecology and Culture, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, 11Ape Social Mind Lab, Institute of Cognitive Science Marc Jeannerod, UMR 5229, CNRS, Lyon, France, 12Taï Chimpanzee Project, Centre Suisse de Recherches Scientifiques, Abidjan, Cote D'ivoire, 13Felix Bloch Institute for Solid State Physics, Faculty of Physics and Earth Sciences, Leipzig University, Leipzig, Germany, 14Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, London, United Kingdom
Synopsis
Keywords: Large Animals, Nonhuman Primates, Neuroscience, Chimpanzee brain
Motivation: To understand the evolutionary development of hand motor cortex specialization and lateralization related to handedness in great apes.
Goal(s): To investigate the cortical motor hand-knob area microstructure, as well as its hemispheric laterality, between chimpanzee and human brains.
Approach: Myelin and iron accumulation were analyzed in hand foot and face cortical regions using high-resolution qMRI brain maps (R2* and MTsat) from 16 chimpanzees post-mortem and 54 humans in vivo.
Results: In both species, qMRI values were higher in the hand field suggesting higher myelin and iron content compared to foot and face fields. Lateralization of measures was only observed in humans.
Impact: The evolution of hand motor skills involves significant changes in cortical microstructure. Our findings provide valuable insights into the anatomical underpinnings of distinct motor behaviors, such as extensive tool use observed in hominids
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
