Keywords: Vascular/Vessel Wall, Cardiovascular, Vertebrobasilar artery geometry
Motivation: Both arterial geometry deformation and hypertension contribute to atherosclerosis development. However, their combined impact has not been explored.
Goal(s): To investigate the combined effects of vertebral artery geometry deformation on vertebrobasilar atherosclerosis in hypertensive patients using high-resolution vessel wall imaging.
Approach: Three-dimensional T1 SPACE magnetic resonance imaging, Student’s t-test, Mann-Whitney U test, and χ² test.
Results: Vertebral artery geometry deformation appears to have an additive effect on the formation of vulnerable plaques in the basilar artery of hypertensive patients.
Impact: Our findings concerning the additive effects of vertebral artery geometry deformation on vulnerable plaques in the basilar artery of hypertensive patients provide a basis for improved clinical management and comorbidity treatment strategies.
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