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Abstract #3665

Additive effects of vertebral artery geometry deformation on VBA plaque vulnerability in hypertension: an HR-VWI study

Jiying Xia1, Chen Zhang2, Lingjun Mei1, Jianbo Lyu1, and Xiaofeng Qu1
1Department of Radiology, the Second Hospital of Dalian Medical University, Dalian, China, 2MR Research Collaboration, Siemens Healthineers, Beijing, China

Synopsis

Keywords: Vascular/Vessel Wall, Cardiovascular, Vertebrobasilar artery geometry

Motivation: Both arterial geometry deformation and hypertension contribute to atherosclerosis development. However, their combined impact has not been explored.

Goal(s): To investigate the combined effects of vertebral artery geometry deformation on vertebrobasilar atherosclerosis in hypertensive patients using high-resolution vessel wall imaging.

Approach: Three-dimensional T1 SPACE magnetic resonance imaging, Student’s t-test, Mann-Whitney U test, and χ² test.

Results: Vertebral artery geometry deformation appears to have an additive effect on the formation of vulnerable plaques in the basilar artery of hypertensive patients.

Impact: Our findings concerning the additive effects of vertebral artery geometry deformation on vulnerable plaques in the basilar artery of hypertensive patients provide a basis for improved clinical management and comorbidity treatment strategies.

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