Abstract #3672

Gadolinium-based contrast agent and stimulated echo acquisition mode cardiac diffusion-weighted imaging: preliminary results

Satonori Tsuneta^1,2, Satoru Aono³, Jihun Kwon⁴, Masami Yoneyama⁴, Hiroki Uehara⁵, Takuya Aoike³, Sakae Takenaka⁵, Hidenori Koyano⁶, Noriyuki Fujima¹, Toshiyuki Nagai⁵, Toshihisa Anzai⁵, Kazuyuki Minowa², and Kohsuke Kudo^7,8

¹Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ²Department of Radiology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan, ³Department of Radiological Technology, Hokkaido University Hospital, Sapporo, Japan, ⁴Philips Japan, Ltd., Tokyo, Japan, ⁵Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁶Technical Support Center, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁷Department of Diagnostic Imaging, Hokkaido University Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁸Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sapporo, Japan

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Advanced cardiac sequences, such as stimulated echo acquisition mode (STEAM) diffusion-weighted imaging (DWI), preferably scan during the interval between gadolinium-based contrast agent (Gd) injection and late gadolinium enhancement to shorten the examination time if possible.

Goal(s): We sought to reveal whether STEAM-DWI could be performed after Gd injection.

Approach: We performed STEAM-DWI on phantoms with different Gd concentrations and heart rates (HRs) and on patients before and after Gd injection.

Results: The signal intensity of STEAM-DWI was affected by both Gd concentration and HR, and the mean apparent diffusion coefficient was less affected by Gd.

Impact: Although the signal intensity of stimulated echo acquisition mode (STEAM) and the precision of apparent diffusion coefficient (ADC) were reduced with gadolinium-based contrast agent (Gd), STEAM diffusion-weighted imaging after Gd injection might be feasible regarding the calculation of mean ADC.

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