Abstract #3674

The Association between Body Composition Patterns and Cardio-Cerebrovascular Disease in the UK Biobank

Tianshu Yang¹, Ying Hu¹, Xu Han¹, Wentao Hu¹, Yongming Dai², and Yan Zhou¹

¹Department of Radiology, Renji hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, ²School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China

Synopsis

Keywords: Atherosclerosis, Atherosclerosis

Motivation: The association between body composition patterns and coexistence of cardiovascular and cerebrovascular diseases (Cardio-Cerebrovascular diseases) remains elusive.

Goal(s): To explore the association between body composition patterns and Cardio-Cerebrovascular diseases.

Approach: We employed multivariate logistic models, restricted cubic spline methods to assess the association between body composition patterns (determined via principal component analysis) and coexisting CSVD-CHD.

Results: Our findings indicate that male gender, high "trunk fat mass", and low "bone density" patterns are associated with higher risk of coexisting CSVD-CHD with gender-specific differences.

Impact: These results highlight the potential of body composition management in reducing the risk of CSVD-CHD coexistence.

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