Keywords: Myocardium, DSC & DCE Perfusion, Ungated Perfusion; Radial SMS;
Motivation: Standard ECG-gated saturation recovery sequences can be limited under arrhythmia. However, few studies have compared the performance of ungated and gated saturation recovery sequences using radial simultaneous multi-slice (SMS) sequences.
Goal(s): To analyze the accuracy and repeatability of ungated and gated radial SMS sequences.
Approach: Pixel-wise myocardial blood flow maps were generated using the Fermi model for five canines and two human subjects. Human studies were performed twice on separate days for repeatability.
Results: The ungated radial SMS saturation recovery sequence can be used to quantify resting perfusion myocardial blood flow with similar accuracy and reproducibility to its ECG-gated counterpart.
Impact: The ungated radial SMS saturation recovery sequence could allow for increased robustness to ECG-related issues commonly seen in atrial fibrillation.
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