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Abstract #3684

A comparison of ungated radial SMS and ECG-gated myocardial perfusion MRI

Johnathan Le1, Jason Mendes1, Andrew Arai2, Ravi Ranjan2, Edward DiBella1, and Ganesh Adluru1
1Utah Center for Advanced Imaging Research, University of Utah, Salt Lake City, UT, United States, 2Division of Cardiology, University of Utah, Salt Lake City, UT, United States

Synopsis

Keywords: Myocardium, DSC & DCE Perfusion, Ungated Perfusion; Radial SMS;

Motivation: Standard ECG-gated saturation recovery sequences can be limited under arrhythmia. However, few studies have compared the performance of ungated and gated saturation recovery sequences using radial simultaneous multi-slice (SMS) sequences.

Goal(s): To analyze the accuracy and repeatability of ungated and gated radial SMS sequences.

Approach: Pixel-wise myocardial blood flow maps were generated using the Fermi model for five canines and two human subjects. Human studies were performed twice on separate days for repeatability.

Results: The ungated radial SMS saturation recovery sequence can be used to quantify resting perfusion myocardial blood flow with similar accuracy and reproducibility to its ECG-gated counterpart.

Impact: The ungated radial SMS saturation recovery sequence could allow for increased robustness to ECG-related issues commonly seen in atrial fibrillation.

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