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Abstract #3695

Feasible and Transferable 3D Quality Control Model for ASL Images

Ruoge Lin1, Jixin Luan2, Aocai Yang2, Manxi Xu2, Guolin Ma2, Sudipto Dolui3, and Li Zhao1
1College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, 2Department of Radiology, China-Japan Friendship Hospital, Beijing, China, 3Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

Synopsis

Keywords: Arterial Spin Labelling, Arterial spin labelling, Image Quality Control

Motivation: Arterial spin labeling (ASL) is vulnerable to motion and has low signal-to-noise ratio, which may cause unusable image quality.

Goal(s): To propose a feasible and transferable quality control model for 3D ASL images across multiple cohorts/sites.

Approach: A novel model was proposed with a long short-term memory network for flexible volume inputs and a domain-adversarial neural network for model generalization, which was validated on two different datasets and the performance was evaluated with and without domain adaptation.

Results: The model achieved 24% and 31% higher accuracy in slice-wise and volume-wise evaluation on the unlabeled target dataset compared to the one without domain adaptation.

Impact: The proposed model enables flexible and transferable quality control for 3D ASL images, which may offer a valuable tool for brain studies across multiple cohorts and sites.

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Keywords