Abstract #3701

Feasibility of Velocity-Selective ASL MRA at 5T

Ziqi Sun¹, Hongwei Li¹, Lixin Liu¹, Xianyi Zhang¹, Jiayu Zhu², Xijing Zhang², Zhensen Chen^1,3, and He Wang^1,3

¹Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ²Central Research Institute, United Imaging Healthcare Group, Shanghai, China, ³MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Fudan University, Shanghai, China

Synopsis

Keywords: Arterial Spin Labelling, Arterial spin labelling

Motivation: Ultra-high field (UHF) provides improved SNR that benefits velocity-selective arterial spin labeling (VSASL) MRA; however, the sensitivity of VS prepulses to B0 and B1 inhomogeneities may render VS ASL MRA impractical.

Goal(s): This study aims to assess the feasibility of VS ASL MRA for human brain at 5T.

Approach: Double-refocused hyperbolic-secant (DRHS) module, B1-independent rotation (BIR)-4 module, and BIR-8 module based VS ASL MRA were implemented and compared at 5T.

Results: The VS ASL MRA utilizing BIR-4 or BIR-8 modules at 5T had decent image quality, although there exist subtraction errors in static tissues.

Impact: The study suggests that VS ASL MRA at 5T is feasible.

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