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Abstract #3726

Multimodal characterization of inter-individual differences during auditory statistical learning

Jenifer Miehlbradt1, David Romascano1, Jonathan Wirsich2, Frederic Grouiller2, and Petra Susan Hüppi1,3
1University of Geneva, Geneva, Switzerland, 2CIBM, Geneva, Switzerland, 3University hospitals of Geneva, Geneva, Switzerland

Synopsis

Keywords: Task/Intervention Based fMRI, fMRI (task based), Learning

Motivation: Learning abilities present important variations across individuals. Yet, learning is often assessed at group levels and in pre/post paradigms.

Goal(s): Our goal was to characterize the cerebral activity sustaining learning using BOLD variability and EEG synchronization, and to associate these patterns with behavioral scores.

Approach: 18 young healthy adults performed an auditory statistical learning task during a joint EEG-fMRI acquisition.

Results: Better learning outcomes were associated with higher temporal BOLD variability, lower BOLD variability in the fusiform, occipital and calcarine gyri, as well as with a higher task-specific synchronization of the right temporal EEG signals.

Impact: We show that BOLD variability and EEG entrainment are appropriate markers to assess learning-specific brain activity patterns. In addition, outcomes from these distinct imaging modalities present similarities in spatial localization and explainability of behavioral outcomes.

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Keywords