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Abstract #3851

Learning temporal characteristics in multi-contrast MR images with self-supervision: An application to accelerating quantitative T2 mapping

Lavanya Umapathy1,2, Haoyang Pei1,2,3, Noam Ben-Eliezer1,2,4, Daniel K Sodickson1,2,5, and Li Feng1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, NYU Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, NYU Grossman School of Medicine, New York, NY, United States, 3Department of Electrical and Computer Engineering and Department of Biomedical Engineering, New York University Tandon School of Engineering, New York, NY, United States, 4Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel, 5Vilcek Institute of Graduate Biomedical Sciences, NYU Grossman School of Medicine, New York, NY, United States

Synopsis

Keywords: AI/ML Image Reconstruction, Machine Learning/Artificial Intelligence, Vision transformer, accelerated parameter mapping, T2 mapping

Motivation: Accurate quantification for parameter mapping requires sufficient sampling of temporal signal evolution. Current DL-based approaches to learn parameter maps with fewer multi-contrast images often rely on fixed input parameters, limiting their flexibility

Goal(s): To learn temporal characteristics of underlying tissues in multi-contrast MR images to provide a flexible DL model for accelerated quantitative T2-mapping.

Approach: A vision transformer (T2-ViT) is combined with masked auto-encoder training to learn model-free T2 signal evolution given random temporal under-sampling.

Results: Given the first three TE images, the model can predict T2w images at longer TE times with high structural similarities and low T2-estimation errors, making acceleration possible.

Impact: An understanding of underlying temporal characteristics of tissues with vision transformers can help with intelligent design of current multi-contrast data acquisition schemes.

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Keywords