Abstract #3903

Application Research of Cellular Microstructural Parameters Based on MRI in Predicting Lymph Node Metastasis and Tumor Deposit in Rectal Cancer

Siqi Yi¹, Xiaolei Dong¹, Yanwan Li², Meining Chen³, and Xiaoli Chen¹

¹Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China, ²"Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China" and "School of Medicine University of Electronic Science and Technology of China", Chengdu, China, ³MR Research Collaboration Siemens Healthineers, Chengdu, China

Synopsis

Keywords: Microstructure, Cancer, Rectal cancer; Tumor deposit; Metastatic lymph nodes; Time-dependent diffusion magnetic resonance imaging; Cellular microstructural parameters

Motivation: During the diagnosis of LNM and TD, conventional MRI only makes judgments from macro-perspectives . However, the td-dMRI can analyze from the perspective of the microstructure of cancer cells.

Goal(s): This study aims to explore the feasibility of predicting LNM and TD based on td-dMRI to obtain the microstructural parameters of cancer cells.

Approach: td-dMRI was used to analyze Vin, d, Dex, and cellularity to predict LNM and TD before surgery.

Results: The microstructural parameter diameter based on td-dMRI has potential in predicting LNM and TD of rectal cancer, and it is expected to provide assistance for the diagnosis and treatment of rectal cancer.

Impact: The parameter diameter derived from td-dMRI has the potential to serve as an imaging biomarker for the preoperative prediction of LNM and TD.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.