Meeting Banner
Abstract #3930

Hippocampal volume alteration in patients with cognitive impairment due to post-COVID-19 condition.

Andrea Dell'Orco1, Lucas Christoph Adam2, Mirja Steinbrenner2, David Steinbart2, Lorenz Friedrich Wilhelm Pechstein2, Christiana Franke2, and Michael Scheel1
1Institute for Neuroradiology, Charité Universitaetsmedizin Berlin, Berlin, Germany, 2Department of Neurology and Experimental Neurology, Charité Universitaetsmedizin Berlin, Berlin, Germany

Synopsis

Keywords: Infectious Disease, COVID-19, post-COVID condition, Hippocampus

Motivation: Assessing brain alterations in post-COVID-19 condition (PCC) can enhance our understanding of the underlying mechanisms driving neurocognitive impairment in this condition. Hippocampal alterations are often related to cognitive impairment, and previous studies have linked these alterations to PCC.

Goal(s): To conduct an exploratory analysis of potential hippocampal volumetric alterations in patients experiencing cognitive impairment due to PCC.

Approach: Comparison of brain volumetric data from Freesurfer Hippocampal Subfield segmentation of patients with PCC to that of healthy controls (HC).

Results: Patients with PCC show reduced bilateral hippocampal volume in most regions of the hippocampal body compared to the HC group.

Impact: Understanding the biological changes associated with PCC advances the identification of underlying mechanisms and could guide the development of effective treatments for this condition.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords