Keywords: Diffusion Analysis & Visualization, Diffusion Analysis and Visualization
Motivation: The goal of study is to improve glioma classification by non-invasively evaluating IDH genotypes through the use of DDVD and habitat analysis. This study emphasizes the examination of tissue perfusion within the tumor microenvironment.
Goal(s): Distinguishing IDH genotypes of diffuse gliomas by applying DDVD analysis across the entire tumor parenchyma and its specific habitats.
Approach: This study employs DWI to collect DDVD metrics from 63 patients diagnosed with gliomas. The DDVD metrics were correlated with IDH genotypes and Ki-67 status.
Results: Significant differences in DDVD were observed between IDH-mutant and IDH-wildtype gliomas. The habitat analysis notably enhanced the diagnostic performance for IDH genotyping.
Impact: This study introduces DDVD as a novel biomarker for non-invasive IDH genotyping in diffuse gliomas, offering valuable insights into tumor biology and advancing the field toward more personalized treatment strategies in neuro-oncology.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords