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Abstract #4145

Pathological Myocardial Strain Analysis Using a Novel Motion Tracking Method in 3D C-MRI

Haizhou Liu1,2, Zhou Liu1, Xueling Qin3, Yuxi Jin2, Wei Cui4, Yijia Zheng1, Hairong Zheng2, Dong Liang2, Jiuping Liang3, Dehong Luo1, and Zhanli Hu2
1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China, 2Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 3Shenzhen Bao'an District Songgang People's Hospital, Shenzhen, China, 4GE Healthcare, MR Research, Beijing, China

Synopsis

Keywords: Visualization, Cardiomyopathy, C-MRI, Motion tracking

Motivation: Very low myocardial contrast in C-MRI lacks sufficient gradient information, preventing effective strain evaluation in feature tracking.

Goal(s): Our goal was to enhance gradient information to achieve 2D and 3D myocardial strain measurement.

Approach: We introduced a novel motion tracking technique integrated with mechanical regularization and tested on two C-MRI datasets.

Results: The motion and strain of ES relative to ED have been accurately quantified, which is approximately 10% higher than existing methods.

Impact: Our novel motion tracking framework enables low-contrast C-MRI to measure 2D/3D myocardial motion accurately, aiding cardiomyopathy classification and precise localization of myocardial dysfunctions.

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Keywords