Keywords: Inflammation, Infiltration, COVID-19
Motivation: Long COVID is associated with a significant prevalence of myocardial injury, yet its detection and classification using advanced imaging remain underexplored.
Goal(s): To assess the feasibility and diagnostic value of hybrid CMR/FDG-PET imaging in detecting and classifying myocardial injury in long COVID patients.
Approach: We applied a multiparametric imaging protocol, using PSIR-LGE, MOLLI 5(3)3 T1, and T2-prepared sequences, alongside FDG-PET, to categorize myocardial involvement as chronic active, healed, or absent.
Results: In 32 patients, hybrid CMR/FDG-PET classified 28% with chronic active injury, 53% with healed injury, and 19% with no injury, providing crucial insights for targeted management in long COVID.
Impact: This study establishes hybrid CMR/FDG-PET as a valuable diagnostic tool for precise myocardial injury characterization in long COVID, enabling tailored treatment strategies. It opens avenues for investigating chronic myocardial inflammation's long-term effects, potentially transforming patient management and outcomes.
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