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Abstract #4193

High-Resolution Diffusion Tensor Imaging with 3D Long-Axis PROPELLER-EPI (3D-LAP-EPI)

Shihui Chen1,2, Hailin Xiong2, Yi Li2, and Hing-Chiu Chang1,2
1Multi-Scale Medical Robotics Center, Hong Kong, China, 2Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China

Synopsis

Keywords: Diffusion Reconstruction, Acquisition Methods, 3D long-axis PROPELLER-EPI, high-resolution diffusion tensor imaging

Motivation: 2D-PROPELLER-EPI takes advantage of higher SNR and reduced geometric distortion compared to single-shot EPI. 3D-PROPELLER-EPI may further improve the through-plane resolution and SNR but at the cost of scan time.

Goal(s): To investigate the effectiveness of the proposed reconstruction and acquisition method for 3D-PROPELLER-EPI in high-resolution diffusion tensor imaging within feasible scan time.

Approach: We proposed a reconstruction framework and highly-accelerated acquisition patterns based on data sharing to achieve robust performance for recovering diffusion-weighted images.

Results: The proposed method produces comparable quality of diffusion-weighted images to those from unaccelerated data using 3D-PROPELLER-EPI.

Impact: This study verifies the feasibility of 3D long-axis PROPELLER-EPI in high-resolution diffusion tensor imaging enabled by the proposed reconstruction framework and the highly-accelerated acquisition patterns based on data sharing along both kz- and diffusion-direction.

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Keywords