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Abstract #4203

Robust Simultaneous Multi-Slice Diffusion Tensor Cardiovascular MRI using Referenceless Nyquist Ghost Correction

Eun ji Lim1,2, Ke Wen1,2, Karl Kunze3, Radhouene Neji3,4, Dudley Pennell1,2, Pedro F Ferreira1,2, Jaeseok Park5, Andrew Scott1,2, and Sonia Nielles-Vallespin1,2
1National Heart and Lung Institute, Imperial College London, London, United Kingdom, 2CMR Unit, Royal Brompton Hospital, London, United Kingdom, 3Siemens Healthineers, London, United Kingdom, 4Biomedical Engineering, King's College London, London, United Kingdom, 5Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of

Synopsis

Keywords: Diffusion Reconstruction, Cardiovascular, Diffusion Tensor Imaging, Simultaneouse Multi-Slice, Image Reconstruction, Nyquist Ghost Correction, Cardiovascular Imaging

Motivation: Simultaneous multislice parallel imaging (SMS-PI) improves diffusion tensor cardiovascular MR (DT-CMR) efficiency but requires multiple calibration scans, prolonging acquisition and risking misalignment from heart movement and image artefacts.

Goal(s): Enhance SMS-PI DT-CMR efficiency and accuracy, while minimising artefacts to improve cardiac microstructure quantification.

Approach: We implemented referenceless EPI ghost correction with 1-step SMS-PI. Comparisons with 2-step, EPI navigator-based methods assessed artefact suppression and diffusion quantification accuracy.

Results: Our SMS method reduced ghost and inter-slice leakage artifacts compared to conventional navigator-based 2-step methods, achieving comparable DT-CMR results to single-band approaches. +++

Impact: One-step SMS reconstruction combined with referenceless EPI phase correction enhances imaging efficiency while suppressing ghost and leakage artefacts, enabling a more robust SMS DT-CMR and paving the way for its clinical translation.

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Keywords