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Abstract #4238

Optimizing the white matter/grey matter contrast on a portable 46 mT MRI scanner

Beatrice Lena1, Chloé F. Najac1, Tom O'Reilly1, Ruben van den Broek1, and Andrew Webb1
1C.J. Gorter MRI Center, Radiology Department, Leids Universitair Medisch Centrum, Leiden, Netherlands

Synopsis

Keywords: Low-Field MRI, Contrast Mechanisms, WM/GM contrast

Motivation: Low-field MRI, known for its accessibility and portability, faces challenges in distinguishing grey matter (GM) from white matter (WM) due to lower signal-to-noise ratios and converging relaxation times.

Goal(s): This study aimed to improve WM/GM contrast in low-field MRI using a T1-weighted sequence with short inversion time (TI).

Approach: T1-weighted sequence with optimized TI (90ms) was used to enhance contrast maintaining good SNR. Other TIs and resolution were also tested.

Results: Results showed consistently high WM/GM contrast across subjects and resolution, with an optimal TI of 90 ms balancing contrast and SNR.

Impact: This study demonstrates that a T1-weighted sequence with optimized inversion time effectively enhances grey-to-white matter contrast in low-field MRI, offering reliable tissue differentiation for different subjects and resolutions.

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