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Abstract #4295

The effect of time-delayed contrast-enhanced T2-FLAIR on the visualization of large-volume brain metastases

Shanshan Du1, Yong Yin1, Dmytro Pylypenko2, and Guanzhong Gong1
1Shandong Cancer Hospital, Jinan, China, 2GE Healthcare, MR Research China, Beijing, China

Synopsis

Keywords: Analysis/Processing, Analysis/Processing

Motivation: Combining CE T2-FLAIR with CE T1WI increased the detection rate of BMs compared to using CE T1WI alone.

Goal(s): We aimed to provide a basis for improving the BMs GTV determination in shorter time.

Approach: Three radiotherapists delineated the tumor on the CE T1WI and CE T2-FLAIR images. ROI-1min, ROI-3min and ROI-5min were fused with ROI-T2-FLAIR in varying combinations. The ROIs volume, DSC, HD, and the SIs of the ROIs were calculated.

Results: The volumes of the fusion ROIs all were slightly increased compared with that of ROI-total, and the fusion ROIs had a DSC range of 0.903-0.917.

Impact: Our results show that combining time-delayed CE T2-FLAIR and CE T1WI enhances BM visualization and GTV segmentation accuracy, allowing quantitative analysis of BM imaging differences in various sequences through GTV volume and shape evaluation.

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Keywords