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Abstract #4319

Improved-Contrast Accelerated 3D Cones LGE using Cardiac Binning and Keyhole-Filtered View Sharing

Jaykumar H. Patel1,2, Calder D. Sheagren1,2, Terenz Escartin1,2, Labonny Biswas2, Jennifer Barry2, and Graham A. Wright1,2
1University of Toronto, Toronto, ON, Canada, 2Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada

Synopsis

Keywords: Arrhythmia, Cardiovascular, Scar Characterization, 3D High-resolution Imaging, 3D Cone Trajectory, Keyhole-view sharing reconstruction

Motivation: To enable faster, high-resolution late gadolinium enhancement (LGE) MRI for detailed myocardial scar visualization, we developed a 3D cone trajectory approach to achieve faster scans with enhanced image quality.

Goal(s): To reduce scan time and improve image sharpness and contrast in 3D Cones LGE MRI, focusing on the clear differentiation of scar tissue.

Approach: We implemented a keyhole-filtered view-sharing reconstruction technique with a 3D Cone sequence to accelerate LGE imaging within in-vivo infarcted pig hearts.

Results: Fast 3D Cone LGE with keyhole-filtered view-sharing reconstruction achieved enhanced scar contrast and edge sharpness, as confirmed by improved differentiation between scar, myocardium, and blood pool.

Impact: This accelerated imaging enables high-quality myocardial scar visualization, improving pre-treatment or real-time intra-treatment planning for MRI-guided cardiac arrhythmia interventions.

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Keywords