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Abstract #4327

Myocardial iron deficiency in renal anemia patients on peritoneal dialysis: A cardiac magnetic resonance T2* mapping study

Shiqi Jin1, Ruoxue Jia1, Kangwei Jin1, Yunzhu Wu2, and Ting Liu1
1The first hospital of China Medical University, Liaoning, China, 2MR Research Collaboration Team, Siemens Healthineers Ltd., Shanghai, China, Liaoning, China

Synopsis

Keywords: Myocardium, Myocardium, T2* mapping

Motivation: Iron deficiency anemia in chronic kidney disease (CKD) increases cardiovascular risk and mortality in peritoneal dialysis (PD) patients.

Goal(s): This study evaluated cardiac iron levels using CMR T2* sequences and assessed their predictive capacity for left ventricular dysfunction (LVSD) in PD patients with anemia.

Approach: Eighty-three end-stage renal disease (ESRD) patients and 41 controls were included. Standardized CMR imaging was used to analyze correlations between myocardial iron, hemoglobin, and LV function.

Results: Anemic patients had higher T2* values, indicating myocardial iron deficiency. This finding was associated with reduced left ventricular ejection fraction, highlighting its significance in LV dysfunction.

Impact: Cardiac magnetic resonance T2* mapping is a valuable technique for quantitatively measuring myocardial iron levels, facilitating earlier diagnosis of iron deficiency, and guiding treatment in peritoneal dialysis patients.

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