Keywords: Myocardium, Cardiovascular, Epicardial adipose tissue, Left ventricular hypertrophy, Myocardial fibrosis
Motivation: The mechanism of left ventricular hypertrophy(LVH) in Hypertension (HTN) remains unclear.
Goal(s): The study aimed to investigate the effect of increased volume index of epicardial adipose tissue(EAT) on LVH in patients with HTN.
Approach: A total of 209 HTN patients and 50 healthy controls, who underwent cardiovascular magnetic resonance (CMR). Restricted cubic splines,binary logistic regression models and mediation analyses were employed to evaluate the association among EAT, CMR parameters and LVH.
Results: EAT, ECV and GLS were independently associated with LVH. The relationship between increased EAT volume and LVH was mediated by ECV, native T1, GLS, GCS, and GRS.
Impact: Increased EAT volume is independently linked to LVH in hypertensive patients, contributing to fibrosis and ventricular dysfunction. Targeting EAT reduction may be an effective strategy to alleviate LVH.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords