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Abstract #4339

Non-dilated Left Ventricular Cardiomyopathy: Non-ischemic Myocardial Scar as Predictor of Adverse Cardiovascular Events

Mengdi Jiang1 and Minjie Lu1
1Department of Magnetic Resonance Imaging, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Synopsis

Keywords: Myocardium, Cardiomyopathy

Motivation: Management of patients with non-ischemic scar/left ventricular (LV) dysfunction in the setting of normal LV volumes is a clinical conundrum due to the lack of data on guiding their management and advice.

Goal(s): This study sought to investigate the association between non-ischemic myocardial scar and long-term outcomes in patients with non-dilated left ventricular cardiomyopathy (NDLVC).

Approach: 386 patients diagnosed as NDLVC by cardiac magnetic resonance were retrospectively recruited in this study.

Results: Overall, in patients with NDLVC, the detection of LGE, notably when it exceeds 4% of the LV mass, was associated with an increased risk of both mechanical and electrical anomalies.

Impact: A larger population with longer follow-up is warranted to confirm this finding and explore optimal treatment decisions according to different risk stratification.

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