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Abstract #4343

Free-breathing 3D high-resolution Dixon late gadolinium enhancement imaging for scar assessment in chronic myocardial infarction at 3T

Lu Lin1, Yubo Guo1, Shihai Zhao1, Keting Xu1, Jing An2, Michaela Schmidt3, Karl-Philipp Kunze4, and Yining Wang1
1Peking Union Medical College Hospital, Beijing, China, 2Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 3Siemens Healthineers AG, Forchheim, Germany, 4Siemens Healthcare Limited, Camberley, United Kingdom

Synopsis

Keywords: Myocardium, Cardiomyopathy

Motivation: Commonly used 2D late gadolinium enhancement (LGE) imaging can suffer from slice misregistration, respiratory ghosts, and spatial resolution constraints.

Goal(s): We aimed to evaluate the clinical feasibility of a free-breathing high-resolution 3D Dixon LGE imaging prototype with image-based navigation on a 3T system.

Approach: Image quality, semiautomatic LGE quantification, and scan time were evaluated and compared between the prototype and conventional breath-held 2D LGE imaging.

Results: Image quality was comparable between techniques. Size and extent of scar were comparable between 3D in-phase and 2D LGE images. The 3D sequence had a significantly shorter mean acquisition time than did the 2D sequence.

Impact: Free-breathing 3D Dixon LGE imaging with image-based navigation is clinically feasible, shows agreement with the 2D reference method, clearly delineates fibrosis and fat infiltration, and can be performed in a shorter scan time than that of the 2D sequence.

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Keywords