Abstract #4411

Toward Ultra-High-Quality-Factor Wireless Masing MRI Sensing

Eduard Chekmenev¹, Isaiah Adelabu¹, Shiraz Nantogma¹, Simon Fleischer², Mustapha Abdulmojeed³, Henri de Maissin⁴, Andreas B. Schmidt^4,5, Soeren Lehmkuhl², Matthew S. Rosen⁶, Stephan Appelt⁷, Chunqi Qian⁸, and Thomas Theis³

¹Wayne State University, Detroit, MI, United States, ²Karlsruhe Institute of Technology, Karlsruhe, Germany, ³Chemistry, North Carolina State University, Raleigh, NC, United States, ⁴Division of Medical Physics, Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ⁵German Cancer Consortium (DKTK), partner site Freiburg, and German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁶Martinos Center for Biomedical Imaging, Harvard Medical School, Charlestown, MA, United States, ⁷RWTH Aachen University, Aachen, Germany, ⁸Radiology, Michigan State University, Lansing, MI, United States

Synopsis

Keywords: New Devices, Contrast Agents

Motivation: There is a number of limitations using conventional MRI sensing relying on spontaneous emission of NMR signals, including the requirements for high-power RF amplifier, limited sampling rate, FID decay according to T₂*.

Goal(s): Our goal is to employ stimulated emission via Radiofrequency Amplification by Stimulated Emission of Radiation (RASER) to address the limitations of conventional MRI.

Approach: Parametric pumping was employed to boost quality factor of a MRI coil using 7T MRI scanner.

Results: We show wireless MRI maser detector, the quality factor of which was enhanced from 75 up to 1,000,000 for RASER applications at 300 MHz that was otherwise not possible.

Impact: Parametric pumping enables stimulated emission or masing of MRI signal under virtually any conditions of hyperpolarized media with inverted polarization, making RASER a universal approach for sensitive detection modality of hyperpolarized media on virtually any MRI scanner.

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