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Abstract #4442

Motion-corrected brain MRI at 64 mT

Yannick Brackenier1,2, Rui Pedro Teixeira3, Lucilio Cordero-Grande4, Emil Ljunberg5,6, Niall J Bourke6, Tomoki Arichi2, Sean Deoni7, Steve CR Williams6, and Joseph V Hajnal1,2
1Biomedical Engineering Department, King's College London, London, United Kingdom, 2Research Department of Early Life Imaging, King's College London, London, United Kingdom, 3Hyperfine, Guilford, CT, United States, 4Biomedical Image Technologies, ETSI Telecomunicación, Universidad Politécnica de Madrid, Madrid, Spain, 5Department of Medical Radiation Physics, Lund University, Malmo, Sweden, 6Department of Neuroimaging, King's College London, London, United Kingdom, 7Bill & Melinda Gates Foundation, Seattle, WA, United States

Synopsis

Keywords: Motion Correction, Acquisition Methods

Motivation: Ultra-low field (ULF) MRI technology offers affordable and accessible imaging but often requires long scan times to achieve sufficient signal-to-noise ratio (SNR). This increases the risk of image degradation and artifact due to patient motion, especially for those who cannot voluntarily remain still.

Goal(s): To enable motion-corrected brain MRI at ULF.

Approach: We combined alignedSENSE, a data-driven motion correction algorithm based on the SENSE model, with the self-navigated DISORDER phase encoding sampling trajectory to correct for within-scan motion. Additionally, we correct for within-scan phase variations that arise from other system imperfections.

Results: The proposed motion+phase correction improved image quality in all cases tested.

Impact: alignedSENSE, combined with phase correction, can effectively improve image quality without increasing scan time in ULF MRI systems without increasing scan time, making them more valuable for clinical use.

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Keywords