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Abstract #4445

SPEN with Non-linear Gradient Implementation using Pulseq

Andreas Holl1, Maxim Zaitsev1, Frank Zijlstra2, and Sebastian Littin1
1Division of Medical Physics, Department of Diagnostic and Interventional Radiology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany, 2Department of Radiology and Nuclear Medicine, St. Olav's University Hospital, Trondheim, Norway, Trondheim, Norway

Synopsis

Keywords: New Trajectories & Spatial Encoding Methods, Acquisition Methods, Spatiotemporal-encoding, SPEN, quadratic gradients, non-linear gradients

Motivation: SPatiotemporal-ENcoding (SPEN) provides an alternative encoding method in MRI by applying a quadratic phase-profile to counteract distortions due to magnetic field inhomogeneities. However, SAR-constraints arising from the use of chirp-RF pulses hinders clinical application.

Goal(s): Overcoming current SAR-constraints of SPEN by inducing a quadratic phase, using non-linear gradients to demonstrate the feasibility for a clinical application.

Approach: Use of a custom-built matrix gradient coil for generating a quadratic phase-profile instead of SAR-intensive chirp-RF pulses.

Results: SPEN with non-linear gradients is possible and delivers comparable results to the chirp-RF pulse method while overcoming its current limitations, demonstrating the potential for clinical application.

Impact: Non-linear gradient-based spatiotemporal-encoding overcomes SAR-limitations resulting from the use of chirp-RF pulses for quadratic phase profile generation, while providing comparable results, making clinical application feasible.

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