Meeting Banner
Abstract #4481

Joint Optimization of Data Sampling and Reconstruction for Highly Accelerated Cartesian 2D+time Hyperpolarized MRI with AutoSamp

Tanner M. Nickles1,2, Cagan Alkan3, Hsin-Yu Chen1, Yaewon Kim1, Peder Larson1,2, John Pauly3, Daniel B. Vigneron1,2, and Jeremy W. Gordon1,2
1Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, 2UC Berkeley-UCSF Graduate Program in Bioengineering, San Francisco, CA, United States, 3Department of Electrical Engineering, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas), Deep Learning, 13C, Joint-Optimization of Sampling and Reconstruction

Motivation: Low-rank recovery reconstruction enables partial fourier (PF) k-space encoding of 2D dynamic variable-resolution hyperpolarized (HP) [1-13C]pyruvate MRI. Asymmetrical PF encoding reduces T2* weighting, while mitigating the loss of resolution caused by under-sampled k-space.

Goal(s): Explore low-rank recovery reconstruction approaches for PF encoding in sparsely sampled matrices (32x32 or 16x16) in2D dynamic [1-13C]pyruvate MRI.

Approach: Retrospective and prospective [1-13C]pyruvate 2D-EPI brain and abdomen datasets were used to evaluate image fidelity of PF low-rank recovery reconstruction approaches.

Results: PF encoding enabled by low-rank recovery reconstruction algorithms increased SNR for HP metabolic images at both fine and coarser resolutions, all while maintaining image fidelity.

Impact: Asymmetrical PF encoding of 2D dynamic HP [1-13C]pyruvate MRI benefits from low-rank recovery reconstruction methods to ensure image fidelity, and to increase SNR by reducing T2* weighting.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords