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Abstract #4586

Free-breathing respiratory-resolved 3D Lung Vasculature MRI at 0.55T with non-rigid motion-corrected reconstruction

Pablo Pino1, Claudia Prieto1,2, and Rene Botnar1,2,3
1iHEALTH - Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, 2School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 3Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile

Synopsis

Keywords: Motion Correction, Lung

Motivation: To leverage low-field MRI to achieve high quality 3D respiratory-resolved lung vasculature imaging, to improve diagnostic capabilities across respiratory phases.

Goal(s): To develop a free-breathing respiratory-resolved 3D lung imaging framework with feasible scan time at 0.55T.

Approach: Data was acquired in 6 healthy subjects on a 0.55T scanner, with three sequences: a bright-blood bSSFP sequence (CMRA), an interleaved bright and black-blood bSSFP sequence (BOOST), and a Proton Density sequence.

Results: A respiratory-resolved reconstruction framework is demonstrated for 6 healthy volunteers acquired with three sequences. The lung vessels and other anatomical structures are clearly delineated across the respiratory phases, from inspiration to end expiration.

Impact: 3D respiratory-resolved lung images at 0.55T may enable diagnostic capabilities across respiratory phases.

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