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Abstract #4630

K-Space Correction of Rapid Hyperpolarized Signal Decay-induced Image Distortion in Hyperpolarized 13C Metabolic MRI

Haruka Fujiwara1, Hiroshi Hirata1, and Shingo Matsumoto1
1Information Science and Technology, Hokkaido University, Sapporo, Japan

Synopsis

Keywords: Image Reconstruction, Hyperpolarized MR (Non-Gas)

Motivation: Substantial hyperpolarized 13C MRI signal changes during k-space data sampling leads to distortions of spatial information after inverse Fourier transformation.

Goal(s): We aim to cancel the effect of rapid hyperpolarized 13C signal decay and improve the accuracy of spatial information in hyperpolarized 13C chemical shift imaging (CSI).

Approach: Effect of rapid decay of hyperpolarized 13C signal on k-space was mathematically estimated and inversely corrected during the CSI image reconstruction.

Results: Effect of rapid decay of hyperpolarized 13C signal on k-space was mathematically estimated and inversely corrected during the CSI image reconstruction.

Impact: Rapid hyperpolarized 13C MRI signal decay during k-space data sampling causes significant distortion of spatial distribution of metabolites, which can be successfully corrected in the post-processing by considering additional the effect of the magnetic field gradients on the decay.

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Keywords