Keywords: DWI/DTI/DKI, Parkinson's Disease
Motivation: The identification and treatment of PD present formidable challenges due to the absence of objective and specific indicators.
Goal(s): Our goal is to explore the potential of multimodal MRI in identifying and treating PD-MCI, providing a more accurate and objective assessment for these patients.
Approach: DTI and fMRI sequences are used to quantitatively assess brain fibers and networks. Through partial least squares and ROC analysis, we investigate the potential of multimodal MRI in differentiating PD-MCI.
Results: Multimodal magnetic resonance imaging provides objective and quantifiable markers for the early differentiation of PD-MCI and the evaluation of cholinergic drug treatment.
Impact: Multimodal MRI provides reliable, objective markers that improve early differentiation of PD-MCI, enabling earlier, more precise interventions and potentially enhancing patient outcomes while reducing healthcare burdens.
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