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Abstract #4688

T1, T1ρ and T2* mapping of menisci using UTE imaging in patients six months after anterior cruciate ligament reconstruction

Martin Krämer1,2, Helena Schulz2, Aayush Nepal2, Nico Faber3, Stephan Oehme4, Tobias Jung4, Georg N Duda3, Felix Güttler1, Jürgen R Reichenbach2, and Nicholas M. Brisson3
1Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, 2Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, 3Julius Wolff Institute, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Berlin, Germany, 4Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany

Synopsis

Keywords: Osteoarthritis, MSK, Meniscus, Osteoarthritis, UTE

Motivation: Anterior cruciate ligament (ACL) and meniscal tears are significant risk factors for the development of post-traumatic osteoarthritis. Quantitative MRI tissue relaxation parameters offer insight into joint tissue integrity.

Goal(s): To compare meniscal relaxation parameters using multi-parametric ultra-short echo-time (UTE) imaging between patients with ACL reconstruction (ACLR) six months after surgery and healthy controls (CON).

Approach: Twenty-one ACLR patients and 17 CON participants underwent 3T MRI using 3D UTE sequences for T1,T1ρ,T2* mapping in four meniscal regions.

Results: ACLR had higher T2* values across all four meniscal regions, higher T1 values in two regions and higher T1ρ values in one region compared to CON.

Impact: UTE-based quantitative MRI enables objective quantification of meniscal integrity – by comparing knees at high risk of developing OA versus healthy knees. Our approach may be used to detect patients with early meniscal degenerative changes, precursing post-traumatic knee osteoarthritis.

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Abstract

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