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Abstract #4811

The Influences of Reconstruction Methods and Number of Blades on ADC Repeatability in Free-breathing Liver DW-PROPELLER-EPI

Qting Wu1, Liyuan Liang1,2, Hailin Xiong1, Lu Wang3, Yi-Jui Liu4, Chang-Hsien Liu5, Chun-Jung Juan5,6, Hsiao‐Wen Chung7, and Hing-Chiu Chang1,2
1Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong, 2Multi-Scale Medical Robotics Center, Shatin, Hong Kong, 3Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, 4Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, 5Department of Medical Imaging, China Medical University Hsinchu Hospital and China Medical University, Hsinchu, Taiwan, 6Department of Computer Science and Information Engineering, National Taiwan University, Taipei, Taiwan, 7Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan

Synopsis

Keywords: Diffusion Reconstruction, Liver, Liver DWI, ADC Measurement

Motivation: The imaging factors associated with the improved ADC repeatability in a free-breathing liver DW-PROPELLER-EPI technique remains unclear.

Goal(s): To evaluate the influences of reconstruction methods and the number of blades on ADC repeatability.

Approach: ADC repeatability and SNR were measured in 20 subjects with the data reconstructed at varying numbers of blades using either iterative CORPUSE or conventional PROPELLER-EPI reconstruction method.

Results: Both ADC repeatability and SNR were positively correlated with number of blades. The data produced by iterative CORPUSE method showed less discrepancy in measured ADC values across different numbers of blades used for reconstruction.

Impact: Increasing the number of blades can more significantly improve the ADC repeatability than increasing the SNR, and therefore providing an insight into optimizing the performance of free-breathing liver DW-PROPELLER-EPI.

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