Abstract #4850

Assessment of Real-Time PRFS Thermometry Feasibility and Accuracy at 0.55 T for Interventional Ablation Procedures and MRI Safety

Luke E. Schepers¹, Abdul H. Ahmed², Eric D. Anttila¹, Nathan Ooms^3,4, Jesse Roll³, Waqas Majeed², Axel J. Krafft⁵, Florian Maier⁵, Hazar Benan Unal⁶, Behzad Sharif⁶, and David C. Gross¹

¹MED Institute, West Lafayette, IN, United States, ²Siemens Medical Solutions USA Inc., Malvern, PA, United States, ³Cook Advanced Technology, West Lafayette, IN, United States, ⁴Health and Human Sciences, Purdue University, West Lafayette, IN, United States, ⁵Siemens Healthineers AG, Erlangen, Germany, ⁶Weldon School of Biomedical Engineering, Purdue University, Indianapolis, IN, United States

Synopsis

Keywords: Thermometry/Thermotherapy, Thermometry, Low-Field, Ablation, Real-time

Motivation: Evaluate the feasibility of proton resonance frequency shift (PRFS) thermometry at 0.55T while assessing achievable accuracy and its potential use in interventional MRI ablation procedures and safety evaluations.

Goal(s): Determine the performance of PRFS thermometry at 0.55T against calibrated fiber-optic temperature probes.

Approach: Perform phase-shift, drift-corrected thermometry on a homogeneous agar/copper sulfate phantom during heating and cooling with simultaneous temperature probe measurements.

Results: Temperature change was measured for up to one hour with drift correction, and measurements correlated well with the fiber-optic probes. The mean difference between measurements was 0.93±0.35°C and average limit of agreement window (±1.96 SD) was 3.86°C.

Impact: This study explored the accuracy of thermometry at 0.55T in simple homogenous phantoms while looking ahead to implementation in iMRI applications. Thermometry at 0.55T has potential for real-time temperature monitoring with a clinically relevant degree of accuracy.

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