Keywords: Gray Matter, Brain
Motivation: Prior research has primarily focused on overall brain atrophy and white matter hyperintensities.
Goal(s): To evaluate the gray-white matter junction tissue volume (gwJTV) damage in Type 2 diabetes mellitus (T2D) patients with and without carotid plaque and its association with several metabolism-related biomarkers.
Approach: A cross-sectional study of 69 T2D patients with (36) or without (33) asymptomatic atherosclerosis was conducted by evaluating the metabolic biomarkers and the gwJTV .
Results: gwJTV was particularly sensitive to changes in these biomarkers. Higher brain tissue volumes were found in participants without plaque compared to those with plaque.
Impact: This study contributes to the field of diabetes and neuroimaging by introducing the concept of gwJTV as a new MRI measure for evaluating brain tissue integrity in T2D patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords