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Abstract #4988

Magnetic Particle Imaging angiography in a human cadaveric perfusion model

Patrick Vogel1,2, Martin A. Rückert1, Joahnna Günther1, Teresa Reichl1, Thomas Kampf1,3, Philipp Gruschwitz4, Anne Marie Augustin4, Jan-Peter Grunz4, Florian Kleefeldt5, Dominik Peter5, Süleyman Ergün6, Thorsten Alexander Bley4, Volker Christian Behr1, Stefan Herz4,7, and Viktor Hartung4
1Experimental Physics 5 (Biophysics), University of Würzburg, Würzburg, Germany, 2Pure Devices GmbH, Rimpar, Germany, 3Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany, 4Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, 5Institute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany, 6General, Visceral, Transplant, Vascular and Pediatric Surgery, Center of Operative Medicine, University Hospital Würzburg, Würzburg, Germany, 7Radiologie Augsburg Friedberg, Augsburg, Germany

Synopsis

Keywords: Hybrid & Novel Systems Technology, Hybrid & Novel Systems Technology, interventional device; intervention; magnetic particle imaging; MPI; hybrid systems;

Motivation: Magnetic Particle Imaging (MPI) is a radiation-free imaging technique particularly appealing for clinical applications, where reducing radiation exposure is crucial.

Goal(s): Investigating the feasibility of MPI for real-time vascular imaging and its potential as a clinically viable imaging tool.

Approach: To simulate real-life conditions, a portable MPI scanner for human application in combination with an X-ray system was tested on human cadaveric specimens with continuous perfusion.

Results: The results demonstrated reliable visualization of femoral arteries with high temporal resolution, underscoring MPI’s potential as a safe, effective complement to traditional vascular imaging. This approach is particularly beneficial for interventional radiology.

Impact: MPI offers a radiation-free alternative for real-time vascular imaging, improving patient safety, especially in sensitive populations. With its high-resolution, dynamic imaging capabilities the integration into clinical settings could reduce/remove ionizing radiation and associated risks in interventional radiology.

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