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Abstract #4991

Coil evaluation for abdominal imaging of hyperpolarized 13C-pyruvate

Mary McLean1,2, Jonathan Birchall1,2, Ines Horvat-Menih1,2, Joshua Kaggie1,2, Titus Lanz3, Adam Morris4, Fraser Robb5, Marta Wylot1,2, Ashley Grimmer1,2, Elizabeth Latimer1,2, Maria Zamora-Morales1,2, Martin Graves1,2, and Ferdia Gallagher1,2
1Radiology, University of Cambridge, Cambridge, United Kingdom, 2Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, United Kingdom, 3Rapid Biomedical GbmH, Rimpar, Germany, 4Neocoil, Pewaukee, WI, United States, 5GE Healthcare, Aurora, OH, United States

Synopsis

Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas)

Motivation: Clamshell coils are widely used for hyperpolarized 13C-MRI but have limitations in obesity and with widely disseminated disease.

Goal(s): To evaluate a 4-rung birdcage in conjunction with 2 receive arrays (25 total channels) with ~50cm coverage.

Approach: Artifacts, SNR and noise correlations were evaluated using phantoms and the performance of the hardware was shown in a hyperpolarized [1-13C]pyruvate volunteer examination.

Results: The transmit efficiency was acceptable, albeit less when the receive arrays were present, and sporadic spikes were observed. The receive arrays showed SNR benefits relative to birdcage T/R and to previous configurations. Good images were obtained in vivo.

Impact: This body multi-channel array setup enables 13C studies of diseases which may otherwise not be evaluable with clamshell coils. For example, ovarian cancer is widely disseminated through the abdomen and obesity is a strong risk factor.

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